Researchers

Learn how researchers succeed with Yewno Discover

Dominik, Michigan State University, PhD Candidate and Teaching Assistant

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Dominik, a doctoral candidate studying online social behaviors, was especially interested in the phenomenon of ‘fear of missing out.’ “Searching the net for ‘fear of missing out,' specifically in a context of research and academia, is a pain. Having these mind maps, which instantly just gave me three theories I was searching for and two new ones I would not have used, this just made my workday four hours shorter.”

 

Gianna, University of Illinois Chicago, Public Health Researcher

Gianna wanted to know more about endocrine disruptors as part of a larger project to study the effect of sugary soda drinks on public health. It was a new topic for her, but it related strongly to something she was working on already. Searching on Yewno helped her quickly get up to speed without sacrificing depth of research, or eliminating serendipitous discovery: “I like seeing other topics and just being able to see something that I’d find interesting - something that I wouldn’t have seen just doing a regular search.” She liked working with the Yewno Discover graph as a visual reference - making concrete connections from the ‘mind map’ that many students will piece together as a part of the regular research process. “Visually, it makes it easier to research more topics, or expand your search-- or just see that there is a link between two things that you wouldn’t think of searching in the first place.

 

Dorian, Scientist and Researcher

Dorian was looking for a better and more effective treatment option for emerging viruses like Severe Acute Respiratory Syndrome (SARS) coronavirus (SARS-CoV), Middle East Respiratory Syndrome coronavirus (MERS-CoV), and Respiratory Syncytial Virus (RSV). Instead of performing lengthy laboratory examinations, Dorian used Yewno’s index of PubMed and millions of other medically-related documents to organize his investigation. After a day searching with Yewno, Dorian discovered a potentially valuable drug compound, which has been used so far in different, gastrointestinal clinical trials. “Based on the theoretical features required to stop replication of the three respective viruses, I was able to propose the chemical entity called 'semapimod' for antiviral testing. Indeed, it turned out that semaspimod inhibits replication of RSV and SARS with clinically reasonable activity. Currently, truth-telling experiments on MERS-CoV are ongoing. Using Yewno technology enables researchers to generate very fast, highly valuable drug-disease proposals, which is a most impressive feature in medical emergency situations.”

 

Serena, Frankfurt University (Germany), Physics Researcher

Serena was interested in looking for new medical applications of three very old drugs: auranofin (an anti-rheumatic agent), Cicletanine (a drug to treat hypertension), and delta-sleep inducing peptide (DSIP). To accomplish this, Serena planned for three months of literature studies. Using Yewno Discover, Serena found excellent solutions after only three weeks: a) auranofin for Hirschsprung’s disease; b) Cicletanine for Leber’s congenital amaurosis; and, c) DSIP for gout. “These results are so convincing and compelling that I am now going with my supervisor to approach the respective key clinical opinion leaders in academia in order to verify the results experimentally. If it works out well, Yewno technology might have contributed dramatically to improve the quality of life in those affected.”

 

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